Public float: Unknown (no public float found in SEC filings).
We plan to present the updated clinical data from Cohort 1C at the ESMO Congress 2026 in October 2026.
SEC timing context:
Cohort 1C is evaluating EIK1003 in combination with paclitaxel for the treatment of patients with platinum-resistant ovarian cancer or patients with HER2-negative breast cancer that have failed hormonal therapy if ER+ or chemotherapy if ER negative.
Public float: Unknown (no public float found in SEC filings).
We plan to present initial clinical data from this trial at the ESMO Congress 2026 in October 2026.
SEC timing context:
We are currently evaluating EIK1005 in a Phase 1/2 trial as monotherapy and in 25 combination with pembrolizumab in participants with advanced solid tumors.
Public float: Unknown (no public float found in SEC filings).
We plan to present the first clinical data from this trial at the ESMO Congress 2026 in October.
SEC timing context:
We are also conducting a Phase 1/2 trial evaluating the safety and efficacy of EIK1004, our selective PARP1 inhibitor designed to penetrate the central nervous system, for the treatment of patients with ovarian, breast, prostate, and pancreatic cancers.
ORION has no confirmed start and end dates for this wording, so it is not compared with filings.
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First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.
Topline results are the main summary results of a clinical trial, released before the full data.A New Drug Application (NDA) or Biologics License Application (BLA) asks the FDA to approve a drug or biologic for sale.