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Harrow (HROW) pipeline and stated timing

Pipeline at a glance

ProgramEventStageStated timingFiling
IHEEZO (QUELL)/data readoutStage not statedin the fourth quarter of 20268-K ·
NATACYNTopline/data readoutStage not statedin the fourth quarter of 20268-K ·
TRIESENCE Phase 3Topline/data readoutPhase 3in early 20278-K ·

Source: ORION, orionbiotechai.com/company/HROW, data as of Oct 17, 2026
https://www.orionbiotechai.com/company/HROW

Nearest upcoming stated timing: IHEEZO (QUELL) · Topline/data readout · in the fourth quarter of 2026

SEC sources last checked .

Programs and stated timing

○ Quote matched to filing (not yet reviewed by founder) · ✓ Checked by founder.

IHEEZO (QUELL)

Matched

Topline/data readoutin the fourth quarter of 2026

Stage: Not stated

Public float: $1,004,000,000 · as of · SEC filing

IHEEZO (QUELL): Topline data from QUELL, a prospective, randomized, multi-center clinical trial evaluating IHEEZO in patients undergoing intravitreal injections, are expected in the fourth quarter of 2026.

8-K · Filed · Last checked

Source details

Accession 0001493152-26-036865

SEC accepted the filing

Topline/data readoutin the fourth quarter of 2026

Stage: Not stated

Public float: $1,004,000,000 · as of · SEC filing

NATACYN®: The first patients were enrolled in an investigator-initiated clinical study during the second quarter, with topline data expected in the fourth quarter of 2026.

8-K · Filed · Last checked

Source details

Accession 0001493152-26-036865

SEC accepted the filing

TRIESENCE Phase 3

Matched

Topline/data readoutin early 2027

Stage: Phase 3SEC filing · “Phase 3”

Public float: $1,004,000,000 · as of · SEC filing

TRIESENCE: The Company’s Phase 3 trial evaluating TRIESENCE for the treatment of ocular inflammation and pain following cataract surgery is on track to fully enroll in 2026, with topline data expected in early 2027.

8-K · Filed · Last checked

Source details

Accession 0001493152-26-036865

SEC accepted the filing

How this date was described over time

Company periods and sentences are quoted as written. A matching disclosure uses the SEC filing date for the same program and event type. As of .

Program / eventStated period and SEC wordingDisclosure in stated period
IHEEZO (QUELL)Clinical resultsin the fourth quarter of 2026
“IHEEZO (QUELL): Topline data from QUELL, a prospective, randomized, multi-center clinical trial evaluating IHEEZO in patients undergoing intravitreal injections, are expected in the fourth quarter of 2026.”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

NATACYNClinical resultsin the fourth quarter of 2026
“NATACYN®: The first patients were enrolled in an investigator-initiated clinical study during the second quarter, with topline data expected in the fourth quarter of 2026.”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

TRIESENCE Phase 3Clinical resultsin early 2027
“TRIESENCE: The Company’s Phase 3 trial evaluating TRIESENCE for the treatment of ocular inflammation and pain following cataract surgery is on track to fully enroll in 2026, with topline data expected in early 2027.”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

“Not compared” means ORION has not matched this wording against a complete set of SEC filings for its period. It says nothing either way about whether a matching filing exists. Wording without exact dates is not given calendar dates.

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Reading these records

First stated window
The timing wording in the earliest company statement located within the sources checked, quoted as written (for example “2H 2026”). An earlier statement may exist outside those sources.
Disclosure date
The date of the filing or company release that disclosed the readout. “None found” means no such disclosure was located in the sources checked. SEC filings were searched through the “SEC filings searched through” date shown.
1H, 2H, 1Q–4Q
First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.

See HROW in the calendar · Review labels and methodology

Topline results are the main summary results of a clinical trial, released before the full data.