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Immatics (IMTX) pipeline and stated timing

Pipeline at a glance

ProgramEventStageStated timingFiling
anzu-cel/data readoutStage not statedin the first half of 20276-K ·
anzu-cel submission—in 20276-K ·
IMA402/IMA401Topline/data readoutStage not statedin 20276-K ·
IMA203CD8Topline/data readoutPhase 1ESMO Congress 20266-K ·
IMA402Topline/data readoutPhase 1ESMO Congress 20266-K ·

Source: ORION, orionbiotechai.com/company/IMTX, data as of Oct 16, 2026
https://www.orionbiotechai.com/company/IMTX

Nearest upcoming stated timing: anzu-cel · Topline/data readout · in the first half of 2027

SEC sources last checked .

Programs and stated timing

○ Quote matched to filing (not yet reviewed by founder) · ✓ Checked by founder.

anzu-cel

Matched

Topline/data readoutin the first half of 2027

Stage: Not stated

Public float: Unknown (no public float found in SEC filings).

The Company expects to disclose topline data from the final PFS analysis in the first half of 2027, followed by a BLA submission in 2027.

SEC timing context:

Immatics’ global, randomized, controlled, multi-center Phase 3 clinical trial, SUPRAME, is currently ongoing to evaluate the efficacy, safety and tolerability of anzu-cel PRAME cell therapy as monotherapy vs. investigator's choice in patients with unresectable or metastatic melanoma who have received prior treatment with a PD-1 immune checkpoint inhibitor.

6-K · Filed · Last checked

Source details

Accession 0001193125-26-354715

SEC accepted the filing

anzu-cel

Matched

NDA/BLA submissionin 2027

Stage: —

Public float: Unknown (no public float found in SEC filings).

The Company expects to disclose topline data from the final PFS analysis in the first half of 2027, followed by a BLA submission in 2027.

SEC timing context:

Immatics’ global, randomized, controlled, multi-center Phase 3 clinical trial, SUPRAME, is currently ongoing to evaluate the efficacy, safety and tolerability of anzu-cel PRAME cell therapy as monotherapy vs. investigator's choice in patients with unresectable or metastatic melanoma who have received prior treatment with a PD-1 immune checkpoint inhibitor.

6-K · Filed · Last checked

Source details

Accession 0001193125-26-354715

SEC accepted the filing

IMA402/IMA401

Matched

Topline/data readoutin 2027

Stage: Not stated

Public float: Unknown (no public float found in SEC filings).

First data from the IMA402/IMA401 combination cohort are expected in 2027.

6-K · Filed · Last checked

Source details

Accession 0001193125-26-354715

SEC accepted the filing

IMA203CD8

Matched

Topline/data readoutESMO Congress 2026

Stage: Phase 1SEC filing · “Phase 1”

Public float: Unknown (no public float found in SEC filings).

Updated Phase 1 data from IMA203CD8 across multiple PRAME-positive solid tumors will be presented at ESMO Congress 2026.

6-K · Filed · Last checked

Source details

Accession 0001193125-26-354715

SEC accepted the filing

Topline/data readoutESMO Congress 2026

Stage: Phase 1SEC filing · “Phase 1b”

Public float: Unknown (no public float found in SEC filings).

Phase 1b data from IMA402 at the RP2D range across multiple cancers will be presented at ESMO Congress 2026.

6-K · Filed · Last checked

Source details

Accession 0001193125-26-354715

SEC accepted the filing

How this date was described over time

Company periods and sentences are quoted as written. A matching disclosure uses the SEC filing date for the same program and event type. As of .

Program / eventStated period and SEC wordingDisclosure in stated period
anzu-celSubmissionin 2027
“The Company expects to disclose topline data from the final PFS analysis in the first half of 2027, followed by a BLA submission in 2027.”

Filed · EX-99.2

Period not started

The stated period has not started yet, so there is nothing to compare.

anzu-celClinical resultsin the first half of 2027
“The Company expects to disclose topline data from the final PFS analysis in the first half of 2027, followed by a BLA submission in 2027.”

Filed · EX-99.2

Period not started

The stated period has not started yet, so there is nothing to compare.

IMA203CD8Clinical resultsESMO Congress 2026
“Updated Phase 1 data from IMA203CD8 across multiple PRAME-positive solid tumors will be presented at ESMO Congress 2026.”

Filed · EX-99.2

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

IMA402Clinical resultsESMO Congress 2026
“Phase 1b data from IMA402 at the RP2D range across multiple cancers will be presented at ESMO Congress 2026.”

Filed · EX-99.2

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

IMA402/IMA401Clinical resultsin 2027
“First data from the IMA402/IMA401 combination cohort are expected in 2027.”

Filed · EX-99.2

Period not started

The stated period has not started yet, so there is nothing to compare.

“Not compared” means ORION has not matched this wording against a complete set of SEC filings for its period. It says nothing either way about whether a matching filing exists. Wording without exact dates is not given calendar dates.

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Reading these records

First stated window
The timing wording in the earliest company statement located within the sources checked, quoted as written (for example “2H 2026”). An earlier statement may exist outside those sources.
Disclosure date
The date of the filing or company release that disclosed the readout. “None found” means no such disclosure was located in the sources checked. SEC filings were searched through the “SEC filings searched through” date shown.
1H, 2H, 1Q–4Q
First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.

See IMTX in the calendar · Review labels and methodology

Topline results are the main summary results of a clinical trial, released before the full data.A New Drug Application (NDA) or Biologics License Application (BLA) asks the FDA to approve a drug or biologic for sale.