ORION Biotech Catalyst Calendar
Menu
Skip to company dates

Rapport Therapeutics (RAPP) pipeline and stated timing

Pipeline at a glance

ProgramEventStageStated timingFiling
RAP-219/data readoutPhase 2October 202610-Q ·
RAP-219Topline/data readoutStage not statedthe fourth quarter of 202610-Q ·
RAP-219 long-acting injectableTopline/data readoutPhase 120278-K ·

Source: ORION, orionbiotechai.com/company/RAPP, data as of Oct 18, 2026
https://www.orionbiotechai.com/company/RAPP

Nearest upcoming stated timing: RAP-219 · Topline/data readout · October 2026

SEC sources last checked .

Programs and stated timing

○ Quote matched to filing (not yet reviewed by founder) · ✓ Checked by founder.

RAP-219 long-acting injectable

Matched

Topline/data readout2027

Stage: Phase 1SEC filing · “Phase 1”

Public float: $275,840,930 · as of · SEC filing

IND-enabling activities for RAP-219's long-acting injectable formulation continue, with initial Phase 1 pharmacokinetic data expected in 2027.

8-K · Filed · Last checked

Source details

Accession 0001193125-26-333853

How this date was described over time

Company periods and sentences are quoted as written. A matching disclosure uses the SEC filing date for the same program and event type. As of .

Program / eventStated period and SEC wordingDisclosure in stated period
RAP-219Clinical resultsthe fourth quarter of 2026
“Data from the open-label trial is expected in the fourth quarter of 2026.”

Filed · 10-Q

Still within period

As of Oct 19, 2026

RAP-219Clinical resultsOctober 2026
“topline results are expected in October 2026.”

Filed · 10-Q

Still within period

As of Oct 19, 2026

RAP-219 long-acting injectableClinical results2027
“IND-enabling activities for RAP-219's long-acting injectable formulation continue, with initial Phase 1 pharmacokinetic data expected in 2027.”

Filed · EX-99.1

Period not started

The stated period has not started yet, so there is nothing to compare.

RAP-219Clinical resultsthe second half of 2026
“Data from the open-label trial is expected in the second half of 2026.”

Filed · 10-Q

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

RAP-219Clinical resultsthe second half of 2026
“Data from the trial is expected to be released in the second half of 2026.”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

RAP-219Clinical resultsthe fourth quarter of 2026
“topline results are now expected in the fourth quarter of 2026”

Filed · 10-Q

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

RAP-219Clinical resultsthe fourth quarter of 2026
“topline results are now expected in the fourth quarter of 2026”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

RAP-219Clinical resultsthe fourth quarter of 2026
“RAP-219 Phase 2 trial in bipolar mania topline results now expected in the fourth quarter of 2026”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

RAP-219 long-acting injectableClinical results2027
“Development of RAP-219’s long-acting injectable formulation continues to advance, with IND-enabling activities underway and initial Phase 1 pharmacokinetic data expected in 2027.”

Filed · EX-99.1

Period not started

The stated period has not started yet, so there is nothing to compare.

RAP-219Clinical resultsthe second half of 2026
“initial data from the OLE are expected in the second half of 2026.”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

RAP-219 long-acting injectableClinical results2027
“Additionally, Rapport continues development of a long-acting injectable (LAI) formulation of RAP-219, with Phase 1 initial PK results expected in 2027.”

Filed · EX-99.1

Period not started

The stated period has not started yet, so there is nothing to compare.

“Not compared” means ORION has not matched this wording against a complete set of SEC filings for its period. It says nothing either way about whether a matching filing exists. Wording without exact dates is not given calendar dates.

Retained founder-checked records

These dated records retain their original scope and check dates.

RAP-219 / bipolar mania Phase 2 · Topline results

Record RAPP-BM-P2 · Clinical results disclosure · Timing changed

Last checked: .

First stated window
“in the first half of 2027”SEC , Exhibit 99.1, filed
Disclosure date
None foundLast checked:

Initial statement

· Checked by founder · SEC 8-K, Exhibit 99.1

Stated period: in the first half of 2027

topline results expected in the first half of 2027

Timing changed

· Checked by founder · SEC 8-K, Exhibit 99.1

Stated period: in the fourth quarter of 2026

topline results are now expected in the fourth quarter of 2026

Timing changed

· Checked by founder · SEC 8-K, Exhibit 99.1

Stated period: in October 2026

topline results expected in October 2026

Timing changed

· Checked by founder · SEC Form 10-Q

Stated period: in October 2026

topline results are expected in October 2026

Context disclosure

· Checked by founder · SEC 8-K, Exhibit 99.1

Enrollment in the Phase 2 trial is progressing well and topline results are now expected in the fourth quarter of 2026, ahead of the previous guidance of first half of 2027.

Exhibit 99.1: Bipolar Mania Phase 2 Trial Topline Results section; sentence beginning Enrollment in the Phase 2 trial

Sources and scope

Company release: · Company original

Company release: · Company original

Company release: · Company original

March 11, 2025 is the earliest date in these four founder-reviewed sources. Earlier RAPP statements in the wider research inventory have not been imported as founder-reviewed records.

The two August 5, 2026 documents are shown separately. Each is compared with the preceding checked date, not with the other document from August 5.

The 2025-03-11 source labels the trial Phase 2a; the later selected sources use Phase 2. The founder confirmed the common bipolar-mania topline event in these four sources.

SEC filings searched through : The founder compared four selected SEC sources on 2026-10-12: the 2025-03-11, 2026-05-07 and 2026-08-05 Exhibit 99.1 statements and the 2026-08-05 Form statement. RAPP's SEC filing list was checked through 2026-10-12: after 2026-08-05 it lists Forms 4, 144 and SC 13G/A and no other filings; none of these reports trial results.

Company press releases checked : The company press-release statements checked are the ones preserved as SEC Exhibit 99.1 in the four reviewed sources. The issuer website archive was not checked.

Checked by founder: .

Corrections

Rapport Therapeutics (RAPP) — RAP-219 / bipolar mania Phase 2 · Topline results: “in the first half of 2027” (SEC 8-K, Exhibit 99.1 2025-03-11); wording changed from “in the first half of 2027” (2025-03-11) to “in the fourth quarter of 2026” (2026-05-07); wording changed from “in the fourth quarter of 2026” (2026-05-07) to “in October 2026” (2026-08-05); wording changed from “in the fourth quarter of 2026” (2026-05-07) to “in October 2026” (2026-08-05). Status Timing changed, checked 2026-10-12. Sources: https://www.sec.gov/Archives/edgar/data/2012593/000095017025036822/rapp-ex99_1.htm | https://www.sec.gov/Archives/edgar/data/2012593/000119312526210324/rapp-ex99_1.htm | https://www.sec.gov/Archives/edgar/data/2012593/000119312526333853/rapp-ex99_1.htm | https://www.sec.gov/Archives/edgar/data/2012593/000119312526333862/rapp-20260630.htm

Retained program pages

Watch RAPP

Or email ORION to ask for this Watch.

Request another SEC timing statement

Suggest an SEC timing statement to add for RAPP. You can include the original filing link in your note. The founder reads each request by hand.

Or email ORION.

Reading these records

First stated window
The timing wording in the earliest company statement located within the sources checked, quoted as written (for example “2H 2026”). An earlier statement may exist outside those sources.
Disclosure date
The date of the filing or company release that disclosed the readout. “None found” means no such disclosure was located in the sources checked. SEC filings were searched through the “SEC filings searched through” date shown.
1H, 2H, 1Q–4Q
First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.

See RAPP in the calendar · Review labels and methodology

Topline results are the main summary results of a clinical trial, released before the full data.A Form 8-K is a report a company files with the SEC to announce a significant event between its regular reports.A Form 10-Q is a company’s quarterly report to the SEC, with unaudited financial statements.