ORION has no confirmed start and end dates for this wording, so it is not compared with filings.
RAP-219 long-acting injectableClinical results
2027
“Development of RAP-219’s long-acting injectable formulation continues to advance, with IND-enabling activities underway and initial Phase 1 pharmacokinetic data expected in 2027.”
ORION has no confirmed start and end dates for this wording, so it is not compared with filings.
RAP-219 long-acting injectableClinical results
2027
“Additionally, Rapport continues development of a long-acting injectable (LAI) formulation of RAP-219, with Phase 1 initial PK results expected in 2027.”
The stated period has not started yet, so there is nothing to compare.
“Not compared” means ORION has not matched this wording against a complete set of SEC filings for its period. It says nothing either way about whether a matching filing exists. Wording without exact dates is not given calendar dates.
Retained founder-checked records
These dated records retain their original scope and check dates.
Enrollment in the Phase 2 trial is progressing well and topline results are now expected in the fourth quarter of 2026, ahead of the previous guidance of first half of 2027.
Exhibit 99.1: Bipolar Mania Phase 2 Trial Topline Results section; sentence beginning Enrollment in the Phase 2 trial
March 11, 2025 is the earliest date in these four founder-reviewed sources. Earlier RAPP statements in the wider research inventory have not been imported as founder-reviewed records.
The two August 5, 2026 documents are shown separately. Each is compared with the preceding checked date, not with the other document from August 5.
The 2025-03-11 source labels the trial Phase 2a; the later selected sources use Phase 2. The founder confirmed the common bipolar-mania topline event in these four sources.
SEC filings searched through : The founder compared four selected SEC sources on 2026-10-12: the 2025-03-11, 2026-05-07 and 2026-08-05 Exhibit 99.1 statements and the 2026-08-05 Form statement. RAPP's SEC filing list was checked through 2026-10-12: after 2026-08-05 it lists Forms 4, 144 and SC 13G/A and no other filings; none of these reports trial results.
Company press releases checked : The company press-release statements checked are the ones preserved as SEC Exhibit 99.1 in the four reviewed sources. The issuer website archive was not checked.
Checked by founder: .
Corrections
Rapport Therapeutics (RAPP) — RAP-219 / bipolar mania Phase 2 · Topline results: “in the first half of 2027” (SEC 8-K, Exhibit 99.1 2025-03-11); wording changed from “in the first half of 2027” (2025-03-11) to “in the fourth quarter of 2026” (2026-05-07); wording changed from “in the fourth quarter of 2026” (2026-05-07) to “in October 2026” (2026-08-05); wording changed from “in the fourth quarter of 2026” (2026-05-07) to “in October 2026” (2026-08-05). Status Timing changed, checked 2026-10-12. Sources: https://www.sec.gov/Archives/edgar/data/2012593/000095017025036822/rapp-ex99_1.htm | https://www.sec.gov/Archives/edgar/data/2012593/000119312526210324/rapp-ex99_1.htm | https://www.sec.gov/Archives/edgar/data/2012593/000119312526333853/rapp-ex99_1.htm | https://www.sec.gov/Archives/edgar/data/2012593/000119312526333862/rapp-20260630.htm
The timing wording in the earliest company statement located within the sources checked, quoted as written (for example “2H 2026”). An earlier statement may exist outside those sources.
Disclosure date
The date of the filing or company release that disclosed the readout. “None found” means no such disclosure was located in the sources checked. SEC filings were searched through the “SEC filings searched through” date shown.
1H, 2H, 1Q–4Q
First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.
Topline results are the main summary results of a clinical trial, released before the full data.A Form 8-K is a report a company files with the SEC to announce a significant event between its regular reports.A Form 10-Q is a company’s quarterly report to the SEC, with unaudited financial statements.