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Scholar Rock Holding (SRRK) pipeline and stated timing

Pipeline at a glance

ProgramEventStageStated timingFiling
SRK-439/data readoutPhase 1second half of 202610-Q ·

Source: ORION, orionbiotechai.com/company/SRRK, data as of Oct 18, 2026
https://www.orionbiotechai.com/company/SRRK

Nearest upcoming stated timing: SRK-439 · Topline/data readout · second half of 2026

SEC sources last checked .

Programs and stated timing

○ Quote matched to filing (not yet reviewed by founder) · ✓ Checked by founder.

How this date was described over time

Company periods and sentences are quoted as written. A matching disclosure uses the SEC filing date for the same program and event type. As of .

Program / eventStated period and SEC wordingDisclosure in stated period
SRK-439Clinical resultssecond half of 2026
“A Phase 1 study of SRK-439 in healthy volunteers is currently underway, with topline data anticipated in the second half of 2026.”

Filed · 10-Q

Still within period

As of Oct 19, 2026

SRK-439Clinical resultssecond half of 2026
“A Phase 1 study of SRK-439 in healthy volunteers is currently underway, with topline data anticipated in the second half of 2026.”

Filed · 10-Q

Still within period

As of Oct 19, 2026

SRK-439Clinical resultssecond half of 2026
“A Phase 1 study evaluating SRK-439 in healthy volunteers is underway, with topline data expected in the second half of 2026.”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

SRK-439Clinical resultssecond half of 2026
“A Phase 1 study of SRK-439 in healthy volunteers is currently underway, with topline data anticipated in the second half of 2026.”

Filed · 10-K

Still within period

As of Oct 19, 2026

SRK-439Clinical resultssecond half of 2026
“A Phase 1 study in healthy volunteers is underway, and topline data are expected in the second half of 2026.”

Filed · 10-K

Still within period

As of Oct 19, 2026

SRK-439Clinical resultssecond half of 2026
“A Phase 1 study evaluating SRK-439 in healthy volunteers is underway, with topline data expected in the second half of 2026.”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

“Not compared” means ORION has not matched this wording against a complete set of SEC filings for its period. It says nothing either way about whether a matching filing exists. Wording without exact dates is not given calendar dates.

Retained founder-checked records

These dated records retain their original scope and check dates.

SRK-439 · topline data

Record SRRK-P2 · Clinical results disclosure · Window open

Last checked: .

First stated window
“in H2 2026”SEC Exhibit 99.1, filed
Disclosure date
None foundLast checked:

Initial statement

· Checked by founder · SEC Exhibit 99.1

Stated period: in H2 2026

SRK-439 Phase 1 trial ongoing in healthy volunteers; topline data expected in H2 2026

Statement retained

· Checked by founder · SEC Exhibit 99.1

Stated period: in the second half of 2026

A Phase 1 study evaluating SRK-439 in healthy volunteers is underway, with topline data expected in the second half of 2026.

Statement retained

· Checked by founder · SEC Exhibit 99.1

Stated period: in the second half of 2026

A Phase 1 study evaluating SRK-439 in healthy volunteers is underway, with topline data expected in the second half of 2026.

Statement retained

· Checked by founder · SEC Form 10-Q

Stated period: in the second half of 2026

A Phase 1 study of SRK-439 in healthy volunteers is currently underway, with topline data anticipated in the second half of 2026.

Statement retained

· Checked by founder · Company press release

Stated period: in late 2026

A Phase 1 study evaluating SRK-439 in healthy volunteers is progressing well with topline data anticipated in late 2026.

Statement retained

· Checked by founder · SEC Exhibit 99.1

Stated period: in late 2026

A Phase 1 study evaluating SRK-439 in healthy volunteers is progressing well with topline data anticipated in late 2026.

Statement retained

· Checked by founder · SEC Form 10-Q

Stated period: in the second half of 2026

A Phase 1 study of SRK-439 in healthy volunteers is currently underway, with topline data anticipated in the second half of 2026.

Sources and scope

Company release: · Company original

Company release: · Company original

Company press release listing · checked

The initial entry means the earliest wording located within the sources checked; an exhaustive history is not asserted.

Company timing wording is retained. A newer corporate release about another program does not establish a results announcement for this trial.

Additional source review: 2026-10-10. Earlier retained sources were reviewed on 2026-10-09; their original source-check dates and scopes are retained.

The August 6 Form covers the quarter ended June 30, 2026.

SEC filings searched through : and Ex-99.1 1/12, 3/3 (incl. 8-K/A), 5/7, 10-Q 5/7, 8-K and Ex-99.1 8/6 checked against originals. Later SEC filings not searched. Supplement reviewed 2026-10-10: selected 2026-08-06 SEC Form 10-Q timing occurrences. This is not an exhaustive later-filing search.

Company press releases checked : Press releases page 1 checked on 10/9; Oct 8 release is apitegromab MAA, not SRK-439.

Checked by founder: .

Corrections

· Display rule corrected — equivalent timing phrases (e.g., 'H2 2026' / 'second half of 2026') are now shown as Statement retained. Source quotes and status unchanged. · Equivalent timing notation is compared after normalization. · Founder approved the normalization correction and this exact public line in this chat on 2026-10-09.

· Added previously omitted 2026-08-06 SEC Form 10-Q timing source. · Selected-source supplement following founder review; prior rows retained. · https://www.sec.gov/Archives/edgar/data/1727196/000119312526336732/srrk-20260630.htm

Scholar Rock (SRRK) — SRK-439 · topline data: “in H2 2026” (SEC Exhibit 99.1 2026-01-12); statement retained “in the second half of 2026” (2026-03-03); statement retained “in the second half of 2026” (2026-05-07); statement retained “in the second half of 2026” (2026-05-07); wording changed from “in the second half of 2026” (2026-05-07) and “in the second half of 2026” (2026-05-07) to “in late 2026” (2026-08-06); wording changed from “in the second half of 2026” (2026-05-07) and “in the second half of 2026” (2026-05-07) to “in late 2026” (2026-08-06); statement retained “in the second half of 2026” (2026-08-06). Status Window open, checked 2026-10-10. Sources: https://www.sec.gov/Archives/edgar/data/1727196/000110465926002757/srrk-20260112xex99d1.htm | https://www.sec.gov/Archives/edgar/data/1727196/000110465926022547/srrk-20260303xex99d1.htm | https://www.sec.gov/Archives/edgar/data/1727196/000110465926056655/srrk-20260507xex99d1.htm | https://www.sec.gov/Archives/edgar/data/1727196/000110465926056667/srrk-20260331x10q.htm | https://investors.scholarrock.com/news-releases/news-release-details/scholar-rock-reports-second-quarter-2026-financial-results-and | https://www.sec.gov/Archives/edgar/data/1727196/000119312526336715/srrk-ex99_1.htm | https://www.sec.gov/Archives/edgar/data/1727196/000119312526336732/srrk-20260630.htm

Retained program pages

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Reading these records

First stated window
The timing wording in the earliest company statement located within the sources checked, quoted as written (for example “2H 2026”). An earlier statement may exist outside those sources.
Disclosure date
The date of the filing or company release that disclosed the readout. “None found” means no such disclosure was located in the sources checked. SEC filings were searched through the “SEC filings searched through” date shown.
1H, 2H, 1Q–4Q
First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.

See SRRK in the calendar · Review labels and methodology

Topline results are the main summary results of a clinical trial, released before the full data.A Form 10-Q is a company’s quarterly report to the SEC, with unaudited financial statements.A Form 8-K is a report a company files with the SEC to announce a significant event between its regular reports.