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Incyte (INCY) pipeline and stated timing

Pipeline at a glance

ProgramEventStageStated timingFiling
INCA033989/data readoutPhase 1second half of 2026EX-99.1 ·
INCA33890Topline/data readoutPhase 1second half of 202610-Q ·
INCB160058Topline/data readoutPhase 1second half of 202610-Q ·
axatilimab + ruxolitinibTopline/data readoutStage not statedsecond half of 202610-Q ·
povorcitinibTopline/data readoutPhase 2second half of 2026EX-99.1 ·
povorcitinibTopline/data readoutPhase 3fourth quarter of 2026EX-99.1 ·
povorcitinibTopline/data readoutStage not statedsecond half of 202610-Q ·
ruxolitinib creamTopline/data readoutPhase 3fourth quarter of 2026EX-99.1 ·
INCB161734 + chemotherapyTopline/data readoutStage not statedsecond half of 202610-Q ·

Source: ORION, orionbiotechai.com/company/INCY, data as of Oct 18, 2026
https://www.orionbiotechai.com/company/INCY

Nearest upcoming stated timing: INCA033989 · Topline/data readout · second half of 2026

SEC sources last checked .

Programs and stated timing

○ Quote matched to filing (not yet reviewed by founder) · ✓ Checked by founder.

INCA033989

Matched

Topline/data readoutsecond half of 2026

Stage: Phase 1SEC filing · “Phase 1”

Public float: $11,200,000,000 · as of · SEC filing

Data from the Phase 1 cohort evaluating INCA033989 as a monotherapy and in combination with ruxolitinib in treatment naïve MF patients are anticipated in the second half of 2026

EX-99.1 · Filed · Last checked

Source details

Accession 0000879169-26-000053

INCA33890

Matched

Topline/data readoutsecond half of 2026

Stage: Phase 1SEC filing · “Phase 1”

Public float: $11,200,000,000 · as of · SEC filing

Additional data from the ongoing Phase 1 study evaluating INCA33890 in combination with bevacizumab and/or chemotherapy in patients with solid tumors is anticipated in the second half of 2026

10-Q · Filed · Last checked

Source details

Accession 0000879169-26-000056

INCB160058

Matched

Topline/data readoutsecond half of 2026

Stage: Phase 1SEC filing · “Phase 1”

Public float: $11,200,000,000 · as of · SEC filing

Results from the Phase 1 trial evaluating INCB160058 in MPN patients with a JAK2V617F mutation are anticipated in the second half of 2026

10-Q · Filed · Last checked

Source details

Accession 0000879169-26-000026

axatilimab + ruxolitinib

Matched

Topline/data readoutsecond half of 2026

Stage: Not stated

Public float: $11,200,000,000 · as of · SEC filing

ruxolitinib in patients with newly diagnosed chronic GVHD is ongoing, with results anticipated in the second half of 2026

10-Q · Filed · Last checked

Source details

Accession 0000879169-26-000056

povorcitinib

Matched

Topline/data readoutfourth quarter of 2026

Stage: Phase 3SEC filing · “Phase 3”

Public float: $11,200,000,000 · as of · SEC filing

Data from the Phase 3 studies (STOP-PN1 and STOP-PN2) evaluating povorcitinib in patients with moderate to severe prurigo nodularis (PN) are anticipated in the fourth quarter of 2026

EX-99.1 · Filed · Last checked

Source details

Accession 0000879169-26-000053

ruxolitinib cream

Matched

Topline/data readoutfourth quarter of 2026

Stage: Phase 3SEC filing · “Phase 3”

Public float: $11,200,000,000 · as of · SEC filing

Topline results from the Phase 3 studies (TRuE-HS1 and TRuE-HS2) evaluating ruxolitinib cream in mild to moderate hidradenitis suppurativa (HS) are anticipated in the fourth quarter of 2026

EX-99.1 · Filed · Last checked

Source details

Accession 0000879169-26-000053

How this date was described over time

Company periods and sentences are quoted as written. A matching disclosure uses the SEC filing date for the same program and event type. As of .

Program / eventStated period and SEC wordingDisclosure in stated period
axatilimab + ruxolitinibClinical resultssecond half of 2026
“ruxolitinib in patients with newly diagnosed chronic GVHD is ongoing, with results anticipated in the second half of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

INCA033989Clinical resultssecond half of 2026
“Data from the Phase 1 cohort evaluating INCA033989 as a monotherapy and in combination with ruxolitinib in treatment naïve MF patients are anticipated in the second half of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

INCA33890Clinical resultssecond half of 2026
“Additional data from the ongoing Phase 1 study evaluating INCA33890 in combination with bevacizumab and/or chemotherapy in patients with solid tumors is anticipated in the second half of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

INCB161734 + chemotherapyClinical resultssecond half of 2026
“treatment in patients with metastatic PDAC is anticipated in the second half of 2026.”

Filed · 10-Q

Still within period

As of Oct 19, 2026

povorcitinibClinical resultssecond half of 2026
“Topline data from the Phase 2 proof-of-concept trial for povorcitinib in asthma are anticipated in the second half of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

povorcitinibClinical resultsfourth quarter of 2026
“Data from the Phase 3 studies (STOP-PN1 and STOP-PN2) evaluating povorcitinib in patients with moderate to severe prurigo nodularis (PN) are anticipated in the fourth quarter of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

povorcitinibClinical resultssecond half of 2026
“additional data from STOP-V1 and STOP-V2 in the second half of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

ruxolitinib creamClinical resultsfourth quarter of 2026
“Topline results from the Phase 3 studies (TRuE-HS1 and TRuE-HS2) evaluating ruxolitinib cream in mild to moderate hidradenitis suppurativa (HS) are anticipated in the fourth quarter of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

axatilimab + ruxolitinibClinical resultssecond half of 2026
“ruxolitinib in patients with newly diagnosed chronic GVHD is ongoing, with results anticipated in the second half of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

axatilimab + ruxolitinibClinical resultssecond half of 2026
“Data from the Phase 2 trial evaluating axatilimab in combination with ruxolitinib in patients with newly diagnosed chronic GVHD are anticipated in the second half of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

INCA033989Clinical resultssecond half of 2026
“Data from the cohort evaluating INCA033989 and INCA033989 in combination with ruxolitinib in treatment naïve MF patients are anticipated in the second half of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

INCA33890Clinical resultssecond half of 2026
“Additional data from the ongoing Phase 1 study evaluating INCA33890 in combination with bevacizumab and/or chemotherapy in patients with solid tumors is expected in the second half of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

INCA33890Clinical resultssecond half of 2026
“Additional data from the ongoing Phase 1 study evaluating INCA33890 in combination with bevacizumab and/or chemotherapy in patients with solid tumors is expected in the second half of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

INCB160058Clinical resultssecond half of 2026
“Results from the Phase 1 trial evaluating INCB160058 in MPN patients with a JAK2V617F mutation are anticipated in the second half of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

povorcitinibClinical resultssecond half of 2026
“data from the Phase 2 proof-of-concept trial for povorcitinib in asthma are anticipated in the second half of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

povorcitinibClinical resultssecond half of 2026
“additional data from STOP-V1 and STOP-V2 in the second half of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

ruxolitinib creamClinical resultsfourth quarter of 2026
“topline results anticipated in the fourth quarter of 2026”

Filed · 10-Q

Still within period

As of Oct 19, 2026

ruxolitinib creamClinical resultsfourth quarter of 2026
“results from the Phase 3 studies (TRuE-HS1 and TRuE-HS2) evaluating ruxolitinib cream in mild to moderate hidradenitis suppurativa (HS) are anticipated in the fourth quarter of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

axatilimab + ruxolitinibClinical resultsearly 2027
“ruxolitinib in patients with newly diagnosed chronic GVHD is ongoing, with results anticipated in early 2027”

Filed · 10-K

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

INCB160058Clinical resultssecond half of 2026
“Results from the Phase 1 trial evaluating INCB160058 in MPN patients with a JAK2V617F mutation are anticipated in the second half of 2026”

Filed · 10-K

Still within period

As of Oct 19, 2026

povorcitinibClinical resultssecond half of 2026
“data from the Phase 2 proof-of-concept trial for povorcitinib in asthma are anticipated in the second half of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

ruxolitinib creamClinical resultsfourth quarter of 2026
“topline results anticipated in the fourth quarter of 2026”

Filed · 10-K

Still within period

As of Oct 19, 2026

ruxolitinib creamClinical resultsfourth quarter of 2026
“results from the Phase 3 studies (TRuE-HS1 and TRuE-HS2) evaluating ruxolitinib cream in mild to moderate hidradenitis suppurativa (HS) are anticipated in the fourth quarter of 2026”

Filed · EX-99.1

Still within period

As of Oct 19, 2026

povorcitinibClinical results2026
“data from the Phase 2 proof-of-concept trial in asthma, are anticipated in 2026”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

povorcitinibClinical resultssecond half of 2025
“data in asthma are anticipated in the second half of 2025”

Filed · 10-Q

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

povorcitinibClinical results2026
“Phase 3 data are anticipated in 2026”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

povorcitinibClinical resultssecond half of 2025
“data in asthma are anticipated in the second half of 2025”

Filed · 10-Q

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

povorcitinibClinical resultssecond half of 2025
“data in asthma are anticipated in the second half of 2025”

Filed · 10-K

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

povorcitinibClinical resultssecond half of 2025
“data in asthma are anticipated in the second half of 2025”

Filed · 10-Q

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

povorcitinibClinical resultssecond half of 2025
“data in asthma are anticipated in the second half of 2025”

Filed · EX-99.1

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

“Not compared” means ORION has not matched this wording against a complete set of SEC filings for its period. It says nothing either way about whether a matching filing exists. Wording without exact dates is not given calendar dates.

Retained company announcements

Historical summaries and source dates are retained separately from the SEC timing quotes above. Earlier publications were collected retrospectively.

Historical catalog checked .

No historical announcement trail is retained for this company in this catalog.

Selected registry record

INCB161734 · NCT07522073

Condition in the selected registry record
Solid Tumors
Phase in the selected registry record
Phase 3
Identity checked

Original ClinicalTrials.gov record · Open the selected study

Retained company–study identity sources

Scope of retained company and registry evidence

These are selected linked records and dated source metadata, not a live registry recheck or the company’s full pipeline. Company announcements and the selected registry study are separate evidence sets. No stage or event timing is borrowed between them.

Coverage and identity checks

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Reading these records

First stated window
The timing wording in the earliest company statement located within the sources checked, quoted as written (for example “2H 2026”). An earlier statement may exist outside those sources.
Disclosure date
The date of the filing or company release that disclosed the readout. “None found” means no such disclosure was located in the sources checked. SEC filings were searched through the “SEC filings searched through” date shown.
1H, 2H, 1Q–4Q
First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.

See INCY in the calendar · Review labels and methodology

Topline results are the main summary results of a clinical trial, released before the full data.