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Revolution Medicines (RVMD) pipeline and stated timing

Pipeline at a glance

ProgramEventStageStated timingFiling
RAS(ON) inhibitor combinations/data readoutStage not statedfourth quarter of 202610-Q ·
RMC-5127Topline/data readoutStage not stated202710-Q ·
daraxonrasibTopline/data readoutPhase 320278-K ·

Source: ORION, orionbiotechai.com/company/RVMD, data as of Oct 13, 2026
https://www.orionbiotechai.com/company/RVMD

Nearest upcoming stated timing: RAS(ON) inhibitor combinations · Topline/data readout · fourth quarter of 2026

SEC sources last checked .

Programs and stated timing

○ Quote matched to filing (not yet reviewed by founder) · ✓ Checked by founder.

RAS(ON) inhibitor combinations

Matched

Topline/data readoutfourth quarter of 2026

Stage: Not stated

Public float: $6,700,000,000 · as of · SEC filing

We currently expect to provide updated combination data in CRC in the fourth quarter of 2026.

10-Q · Filed · Last checked

Source details

Accession 0001193125-26-335104

daraxonrasib

Matched

Topline/data readout2027

Stage: Phase 3SEC filing · “Phase 3”

Public float: $6,700,000,000 · as of · SEC filing

Enrollment in the global Phase 3 RASolve 301 trial evaluating daraxonrasib in patients with previously treated RAS mutant NSCLC is expected to be completed this year, supporting an anticipated initial readout in 2027.

8-K · Filed · Last checked

Source details

Accession 0001193125-26-335039

How this date was described over time

Company periods and sentences are quoted as written. A matching disclosure uses the SEC filing date for the same program and event type. As of .

Program / eventStated period and SEC wordingDisclosure in stated period
daraxonrasibClinical results2027
“Enrollment in the global Phase 3 RASolve 301 trial evaluating daraxonrasib in patients with previously treated RAS mutant NSCLC is expected to be completed this year, supporting an anticipated initial readout in 2027.”

Filed · EX-99.1

Period not started

The stated period has not started yet, so there is nothing to compare.

RAS(ON) inhibitor combinationsClinical resultsfourth quarter of 2026
“We currently expect to provide updated combination data in CRC in the fourth quarter of 2026.”

Filed · 10-Q

Still within period

As of Oct 19, 2026

RMC-5127Clinical results2027
“share initial clinical data in 2027.”

Filed · 10-Q

Period not started

The stated period has not started yet, so there is nothing to compare.

RAS(ON) inhibitor combinationsClinical results2026
“We currently expect to provide updated combination data in CRC in 2026.”

Filed · 10-Q

Not compared

ORION has no confirmed start and end dates for this wording, so it is not compared with filings.

“Not compared” means ORION has not matched this wording against a complete set of SEC filings for its period. It says nothing either way about whether a matching filing exists. Wording without exact dates is not given calendar dates.

Retained program pages

Retained company announcements

Historical summaries and source dates are retained separately from the SEC timing quotes above. Earlier publications were collected retrospectively.

Historical catalog checked .

No historical announcement trail is retained for this company in this catalog.

Selected registry record

daraxonrasib · NCT07252232

Condition in the selected registry record
Pancreatic Cancer
Phase in the selected registry record
Phase 3
Identity checked

Original ClinicalTrials.gov record · Open the selected study

Retained company–study identity sources

Scope of retained company and registry evidence

These are selected linked records and dated source metadata, not a live registry recheck or the company’s full pipeline. Company announcements and the selected registry study are separate evidence sets. No stage or event timing is borrowed between them.

Coverage and identity checks

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Reading these records

First stated window
The timing wording in the earliest company statement located within the sources checked, quoted as written (for example “2H 2026”). An earlier statement may exist outside those sources.
Disclosure date
The date of the filing or company release that disclosed the readout. “None found” means no such disclosure was located in the sources checked. SEC filings were searched through the “SEC filings searched through” date shown.
1H, 2H, 1Q–4Q
First or second half, or first to fourth quarter, of the year named, as the company wrote it. Equivalent notations are compared together; the original wording stays visible.
SEC original
The filing as published on the SEC EDGAR system. “Company original” is the release on the company's own investor site.
Status
One of seven labels set by founder review of the original filings. Definitions: Methodology.

See RVMD in the calendar · Review labels and methodology

Topline results are the main summary results of a clinical trial, released before the full data.